Most series of biopsies of mammographically identified breast lesions
are performed in specialized units following mass screening and report
an 11% to 36% rate of carcinoma. The results of such biopsies in a di
strict hospital setting are analysed. Seventy-nine consecutive needle
localisation biopsies were performed over a 2.5-year period by 15 surg
eons and retrospectively reviewed. 13 lesions (16%) were referred by t
he National Breast Screening Programme. Carcinomas were found on 24 bi
opsies (30%): 8 were in situ and 16 were infiltrative, 5 of whom were
less than 0.5 cm. Thus half of them met the criteria of ''minimal'' ca
rcinoma as described by GALLAGHER. 40% of women 50 years and older and
13% of women less than 50 years had carcinoma. 6% of the lesions read
on mammogram as ''probably'' benign and 47% of those considered as ''
probably'' malignant were cancer. There was no significant correlation
between the mammographic appearance and the occurrence of cancer but
all ''minimal'' invasive carcinomas were associated with calcification
s. Complete removal of the lesion failed in 3 cases. Localisation biop
sy can be performed in a district hospital by general surgeons with a
similar yield of malignancies as in specialized unit and with a high i
ncidence of early detected cancers.