The nephroblastoma-like adenoma of the kidney is an extremely rare tum
or with similarities to the nephroblastoma (Wilm's tumor) of the adult
. In the literature, different terms are applied to these lesions. We
present the case of a 64-year-old woman who underwent a nephrectomy fo
r suspicion of renal cell carcinoma. Histologically the tumor consiste
d of tubular and papillary formations of monomorphic tumor cells witho
ut mitoses or cell-atypias and showed no fibrous capsule. The differen
tial diagnosis to the nephroblastoma of the adult was difficult. Immun
ohistochemically the tumor expressed the embryonic form of the neural
cell adhesion molecule (N-CAM) interstitially and not in the epithelia
l tumor cell as seen in Wilm's tumor. For the biologic tumor-definitio
n it is important to collect and follow these very rare cases.