IN-VITRO ACTIVITIES OF OPC-17116, A NEW QUINOLONE - OFLOXACIN - AND SPARFLOXACIN AGAINST CHLAMYDIA-PNEUMONIAE

Authors
ROBLIN PM MONTALBAN G HAMMERSCHLAG MR
Citation
Pm. Roblin et al., IN-VITRO ACTIVITIES OF OPC-17116, A NEW QUINOLONE - OFLOXACIN - AND SPARFLOXACIN AGAINST CHLAMYDIA-PNEUMONIAE, Antimicrobial agents and chemotherapy, 38(6), 1994, pp. 1402-1403
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
38
Issue
6
Year of publication
1994
Pages
1402 - 1403
Database
ISI
SICI code
0066-4804(1994)38:6<1402:IAOOAN>2.0.ZU;2-C
Abstract
The in vitro susceptibilities of 12 strains of Chlamydia pneumoniae to a new quinolone, OPC-17116; ofloxacin; and sparfloxacin were determin ed. OPC-17116 was slightly less active than sparfloxacin but more acti ve than afloxacin, with a MIC for 90% of strains tested and a minimal chlamydiacidal concentration for 90% of strains tested of 0.5 mu g/ml.