C. Uneyama et al., BIOLOGICAL ACTIONS OF PURINES ON RAT MEGAKARYOCYTES - POTENTIATION BYADENINE OF THE PURINOCEPTOR-OPERATED CYTOPLASMIC CA2+ OSCILLATION, British Journal of Pharmacology, 112(2), 1994, pp. 349-351
We have found that adenine enhanced the purinoceptor-operated cytoplas
mic Ca2+ oscillation in rat megakaryocytes at submillimolar concentrat
ions. Guanine and other nucleic acid bases had no effect on this syste
m. Adenine enhanced the reaction intensity but had no effect on the th
reshold concentration of ATP to evoke the oscillation.