ACTIVATED PROTEIN-C RESISTANCE ASSAY WHEN APPLIED IN THE GENERAL-POPULATION

Authors
ALTES A SOUTO JC MATEO J BORRELL M FONTCUBERTA J
Citation
A. Altes et al., ACTIVATED PROTEIN-C RESISTANCE ASSAY WHEN APPLIED IN THE GENERAL-POPULATION, American journal of obstetrics and gynecology, 176(2), 1997, pp. 358-359
Citations number
2
Categorie Soggetti
Obsetric & Gynecology
Journal title
American journal of obstetrics and gynecology → ACNP
ISSN journal
00029378
Volume
176
Issue
2
Year of publication
1997
Pages
358 - 359
Database
ISI
SICI code
0002-9378(1997)176:2<358:APRAWA>2.0.ZU;2-6
Abstract
We estimated the predictive values of activated protein C resistance i n the diagnosis of women who are carriers of factor V Leiden. When the prevalence of factor V Leiden is 2%, the positive predictive value is 44% and the cost of preventing one thromboembolic death is $44,180,00 0. Thus the activated protein C resistance assay is not cost-effective in ruling out factor V Leiden in this population.