ENZYMATIC-SYNTHESIS OF AMINO-ACID ESTER OF BUTYL ALPHA-D-GLUCOPYRANOSIDE

Authors
FABRE J PAUL F MONSAN P BLONSKI C PERIE J
Citation
J. Fabre et al., ENZYMATIC-SYNTHESIS OF AMINO-ACID ESTER OF BUTYL ALPHA-D-GLUCOPYRANOSIDE, Tetrahedron letters, 35(21), 1994, pp. 3535-3536
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
21
Year of publication
1994
Pages
3535 - 3536
Database
ISI
SICI code
0040-4039(1994)35:21<3535:EOAEOB>2.0.ZU;2-Y
Abstract
The regiospecific enzymatic esterification of butyl alpha-D-glucopyran oside with trichloro 2,2,2 ethyl N-tBoc 4-amino butyrate was achieved using Lipozyme(R) avoiding time consuming protection-deprotection step s. The tBoc group was subsequently removed using trifluoroacetic acid, leading to the formation of butyl 6-0-(4-amino butyroyl)-alpha-D-gluc opyranoside.