THE PROPERTIES OF LIPOSOMES OBTAINED WITH THE HELP OF POLYSORB-1

A systematic study of the conditions of liposome preparation by the me thod of detergent adsorption onto porysorb-I has been carried out. Opt imum conditions have been found for production of stable liposomes wit h a mean size exceeding 100 nm. By means of amperometric checking it h as been shown that the liposome preparations contain two fractions wit h different permeability. The relation between these fractions depends on the conditions of vesicle preparation. Preference has been found i n binding the phospholipid mixture components on the adsorbent. It is shown that this type of liposomes could be use for measurement of the porin content in mitochondrial membranes.