Two hundred and seventy seven Saudi women were prospectively evaluated
post-partum to determine the frequency of post-partum thyroiditis. Fo
ur to six weeks after delivery, 12 (4.3%) had positive antimicrosomal
antibodies and 8 (2.9%) had positive antithyroglobulin antibodies. At
6-8 weeks post-partum, out of 82 subjects followed up, 4 (4.9%) had po
sitive antimicrosomal antibodies and 1 (1.2%) had positive antithyrogl
obulin antibodies. At 8-12 weeks post-partum, out of 70 subjects, anti
microsomal antibodies were detected in 5 (3.5%) subjects and antithyro
globulin in 2 (1.4%). Their routine thyroid function tests (T3, T4, an
d TSH) remained within the normal range. There was no clinical evidenc
e of hyper- or hypothyroidism in any of hte patients during the follow
up. Post-partum thyroiditis, appears to be relatively uncommon in Sau
di Arabia. It does not produce any clinical illness or cause significa
nt subclinical thyroid dysfunction.