S. Moiniche et al., THE EFFECT OF BALANCED ANALGESIA ON EARLY CONVALESCENCE AFTER MAJOR ORTHOPEDIC-SURGERY, Acta anaesthesiologica Scandinavica, 38(4), 1994, pp. 328-335
Forty-two patients scheduled for total knee arthroplasty (n = 20) or h
ip arthroplasty (n = 22) were randomly allocated to receive either con
tinuous epidural bupivacaine/morphine for 48 h postoperatively plus or
al piroxicam, or general anaesthesia followed by a conventional intram
uscular opioid and acetaminophen regimen. Patients undergoing knee- or
hip arthroplasty treated with epidural analgesia had significantly lo
wer pain scores during mobilization under the 48 h epidural infusion c
ompared with patients receiving conventional treatment, while no impor
tant differences were observed after cessation of the epidural regimen
. However, the achieved pain relief had no impact on postoperative con
valescence parameters, such as ambulation, patient activity including
need for nursing care, fatigue or hospital stay. Late postoperative pa
in, fatigue and conservative attitudes and routines in the postoperati
ve care, were the most important reasons limiting mobilization and act
ivity. We conclude that effective early (48 h) postoperative pain reli
ef with balanced analgesia does not per se lead to important improveme
nts in convalescence and hospital stay.