The recent introduction of a new generation of antifungal drugs promis
es to alter significantly therapy for both systemic and superficial my
coses, in particular, onychomycosis. This article presents an in-depth
review of the azoles (the triazoles itraconazole and fluconazole), th
e allylamines (naftifine and terbinafine), and the morpholine derivati
ve amorolfine.