MALIGNANT HYPERTHERMIA-INDUCED BY GENERAL-ANESTHESIA FOR BONE-MARROW HARVESTING

We present a case of a bone marrow donor who developed rhabdomyolysis, acute renal failure and pulmonary edema following an apparently uneve ntful general anesthesia for bone marrow harvesting, Because malignant hyperthermia (MH) was suspected, he was treated with dantrolene, flui d loading, and continuous hemodiafiltration along with symptomatic sup portive care, He made a full recovery and was discharged 3 weeks after harvest, Although the incidence of MH is low, marrow donation involve s the risks of anesthesia as is seen in this case, Close monitoring is required to prevent life-threatening complications associated with th e bone marrow harvesting procedure.