Kh. Vanhoeven et al., PULMONARY METASTASIS FROM HISTOLOGICALLY BENIGN GIANT-CELL TUMOR OF BONE - REPORT OF A CASE DIAGNOSED BY FINE-NEEDLE ASPIRATION CYTOLOGY, Acta cytologica, 38(3), 1994, pp. 410-414
The cytologic features of pulmonary metastasis from a histologically b
enign giant cell tumor of bone are reported. The patient had undergone
curettage of a benign giant cell tumor of the humerus two years earli
er. Aspiration of a pulmonary mass yielded a cellular population of mo
nonuclear stromal cells admixed with a smaller population of binucleat
e forms and occasional giant cells. Vacuolation and granulation of the
stromal cells are cytologic features seen commonly in giant cell tumo
rs of bone, but in the lung these features may deceptively mimic the a
ppearance of pulmonary macrophages, Video thoracoscopic wedge resectio
n of the metastatic lesion was performed subsequently.