PERIPHERAL SENSORY NEUROPATHY ASSOCIATED WITH 1,1,1-TRICHLOROETHANE

A case is described of peripheral sensory neuropathy in a woman who ha d daily exposure to 1,1,1-trichloroethane, used as a degreasing agent. Although previous reviews of the health effects of 1,1,1-trichloroeth ane have not indicated long-term neurotoxicity, there are recent anima l studies that suggest chronic central neurotoxic effects and previous case reports of peripheral neuropathy in three exposed workers in one plant. Our case provides additional evidence that 1,1,1-trichloroetha ne exposure may be associated with peripheral sensory neuropathy. Repo rting of similar cases is encouraged and investigation of the neurotox ic effects of 1,1,1 -trichloroethane is recommended.