C. Vonnumers et al., A KNOWLEDGE-BASED SYSTEM USING FUZZY INFERENCE FOR SUPERVISORY CONTROL OF BIOPROCESSES, Journal of biotechnology, 34(2), 1994, pp. 109-118
In this paper, a rule-based, real-time knowledge based system for biop
rocess fault diagnosis and control is described. The system was design
ed to generate on-line advice for the operators and to supervise autom
atic control of bioprocesses, using biotechnical production of lactic
acid as an example process. It consists of a real-time data acquisitio
n and data processing system linked to a fuzzy expert system written i
n Smalltalk V/Mac. The expert knowledge was expressed in the form of a
rule-based knowledge network, fuzzy membership functions and control
strategies. The fuzzy expert system carries out on-line fault diagnosi
ng on the basis of filtered specific rates calculated from process var
iable measurements, and provides suitable countermeasures to recover t
he process. Fault diagnosis was realized both by backward and forward
chaining procedures. The system was constructed to allow three differe
nt control strategies (given here in Smalltalk syntax), change of Setp
oint, FuzzyAnswer for each discovered fault, employing the fuzzy mean
defuzzification method, and linguistic Advice to the operator. The sys
tem was successfully tested on-line with a laboratory scale process.