X-RAY, NMR, AND THEORETICAL-STUDIES OF THE NOOTROPIC AGENT BMY-21502,A PYRROLIDINONE DERIVATIVE

The preferred crystalline, solution, and in vacuo arrangements of pyri midinyl]-4-piperidinyl]methyl]-2-pyrrolidinone (BMY-21502) were invest igated by means of single-crystal X-ray diffraction, H-1 and C-13 NMR spectroscopy, and semiempirical molecular orbital and molecular mechan ics calculations. The X-ray powder diffraction pattern is also reporte d.