OLFACTORY NEURONS EXPRESSING DISTINCT ODORANT RECEPTOR SUBTYPES ARE SPATIALLY SEGREGATED IN THE NASAL NEUROEPITHELIUM

Authors
STROTMANN J WANNER I HELFRICH T BECK A MEINKEN C KUBICK S BREER H
Citation
J. Strotmann et al., OLFACTORY NEURONS EXPRESSING DISTINCT ODORANT RECEPTOR SUBTYPES ARE SPATIALLY SEGREGATED IN THE NASAL NEUROEPITHELIUM, Cell and tissue research, 276(3), 1994, pp. 429-438
Citations number
30
Categorie Soggetti
Cytology & Histology
Journal title
Cell and tissue research → ACNP
ISSN journal
0302766X
Volume
276
Issue
3
Year of publication
1994
Pages
429 - 438
Database
ISI
SICI code
0302-766X(1994)276:3<429:ONEDOR>2.0.ZU;2-V
Abstract
In situ hybridization techniques have been employed to explore the olf actory epithelium of the rat for the distribution of odorant receptor gene transcripts. We demonstrate that olfactory neurone subpopulations expressing distinct receptor subtypes are spatially segregated within the olfactory epithelium. A compartmentalization of the neuroepitheli um into distinct expression zone is apparent, cells expressing a speci fic receptor are randomly distributed within a given zone. Structurall y related receptor subtypes share a common distribution pattern.