EFFECT OF PH, AGITATION AND AERATION ON HYALURONIC-ACID PRODUCTION BYSTREPTOCOCCUS-ZOOEPIDEMICUS

Authors
JOHNS MR GOH LT OEGGERLI A
Citation
Mr. Johns et al., EFFECT OF PH, AGITATION AND AERATION ON HYALURONIC-ACID PRODUCTION BYSTREPTOCOCCUS-ZOOEPIDEMICUS, Biotechnology letters, 16(5), 1994, pp. 507-512
Citations number
8
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
5
Year of publication
1994
Pages
507 - 512
Database
ISI
SICI code
0141-5492(1994)16:5<507:EOPAAA>2.0.ZU;2-A
Abstract
The optimum pH for both the rate of production and yield of hyaluronic acid (HA) by Streptococcus zooepidemicus from glucose medium was 6.7 +/- 0.2 under anaerobic conditions. High agitation rates (600 rpm) gav e superior results compared to 300 rpm. Aeration of the culture (0.3 V VM) improved the HA yield, but not the rate of production and lead to some acetate and CO2 being formed, in addition to lactate and HA.