In a retrospective, nonblind review of MR imaging of 15 benign periphe
ral nerve neoplasms in 13 patients, the signal pattern of the tumors (
including contrast-enhanced images) and stage were assessed. One lesio
n was subcutaneous, 9 intramuscular, 2 intermuscular and 3 extracompar
tmental. One lesion was located to the trunk, 5 to the upper extremity
and 9 to the lower. The signal on T1-weighted spin-echo images was ho
mogeneous isointense compared to adjacent muscle in 11 lesions and in
2 slightly hyper- and in 2 slightly hypointense. T2-weighted spin-echo
images, acquired in all but one examination, showed a hyperintense si
gnal, homogeneous in 8 and centrally inhomogeneous in 6 lesions. Postc
ontrast T1-weighted images of 11 lesions showed a strong signal, with
an inhomogeneous enhancement in the center of the lesion similar to th
at obtained in T2-weighted images. In 2 cases there were signal charac
teristics indicating bleeding in the tumor. In one lesion both the non
enhanced and contrast-enhanced T1-weighted images showed a hypointense
signal in the tumor center suggestive of intramuscular myxoma. All le
sions were well delineated without reactive edema. In all cases, anato
mic tumor location was correctly assessed. Although the findings were
not pathognomonic for neurinoma, MR imaging provided valuable informat
ion confirming the clinical and cytologic assessments.