S. Kawaii et al., EFFECTS OF CHAVICOL ON INTRACELLULAR IONIZED CALCIUM IN A FREE-LIVINGSOIL NEMATODE, CAENORHABDITIS-ELEGANS, Bioscience, biotechnology, and biochemistry, 58(5), 1994, pp. 982-985
The physiological effects of two phenolic nematocides, chavicol and de
methyleugenol, on C. elegans were studied by [Ca2+](i) measurement usi
ng a microspectrofluorometer and an image analyzer. Chavicol and demet
hyleugenol, which had similar effects on the nematodes, caused a signi
ficant elevation of [Ca2+](i) in the intestinal tract. The image analy
sis suggested that these phenolic nematocides caused the destruction o
f cell membrane and the leakage of cytosol from the intestinal tract i
nto the pseudocoelomic cavity.