Cr. Soccol et al., POTENTIAL OF SOLID-STATE FERMENTATION FOR PRODUCTION OF L(-LACTIC ACID BY RHIZOPUS-ORYZAE()), Applied microbiology and biotechnology, 41(3), 1994, pp. 286-290
Production of L(+)-lactic acid by Rhizopus oryzae NRRL 395 was studied
in solid medium on sugar-cane bagasse impregnated with a nutrient sol
ution containing glucose and CaCO3. A comparative study was undertaken
in submerged and solid-state cultures. The optimal concentrations in
glucose were 120 g/l in liquid culture and 180 g/l in solid-state ferm
entation corresponding to production of L(+)-lactic acid of 93.8 and 1
37.0 g/l, respectively. The productivity was 1.38 g/l per hour in liqu
id medium and 1.43 g/l per hour in solid medium. However, the fermenta
tion yield was about 77% whatever the medium. These figures are signif
icant for L(+)-lactic acid production.