Background: Though rarely reported, mucin deposition may be observed i
n scleroderma. Objective: To verify the frequency of significant amoun
ts of mucin in the biopsy specimens. Methods: Biopsies from 20 patient
s with scleroderma were reviewed and stained to verify the presence of
mucin. Results: Mucin deposits were found in all of the 20 specimens.
Conclusion: Mucin deposition is probably a constant feature in both m
orphea and systemic scleroderma. Its relevance in differential diagnos
is between scleredema and scleroderma is debatable.