DYSPHASIA ACCOMPANIED BY PERIODIC LATERALIZED EPILEPTIFORM DISCHARGES

We encountered a 67-year-old man who presented with repetitious dyspha sia accompanied by periodic lateralized epileptiform discharges (PLEDs ) on the electroencephalogram. A good correlation was established betw een the dysphasia and the PLEDs, A persistent partial seizure accompan ied by PLEDs originating in the left hemisphere presented with dysphas ia clinically, None of the previously reported patients with epileptic dysphasia had accompanying PLEDs, The administration of carbamazepine was successful to terminate the seizure, however valproate was not, T his case indicates that PLEDs may produce significant, however reversi ble, functional damage, and may advance our understanding of the patho physiology of epileptic dysphasia.