A study of Burkitt's lymphoma (BL) in Papua New Guinea for the years 1
958-87 revealed four instances of familiar BL. Incident cases occurred
within 1 year of each other in the four families. Personal follow-up
was possible for three of these families whose pedigrees showed that t
wo or more siblings were affected. There was no significant variation
of the incidence of BL by year of diagnosis or month of onset. There w
as significant variation in annual average incidence of BL between the
three provinces studied, with the highest incidence in the Nuku and L
umi census districts (of the West Sepik Province). This is the first r
eport of familial BL outside Africa.