INVESTIGATIONS TO THE LIPOPOLYSACCHARIDE STRUCTURE OF HAEMOPHILUS-PARASUIS STRAINS IN SDS-PAGE

The LPS patters of 231 H.p. strains were studied by using SDS-PAGE. Th e strains were isolated from the nasal mucous membrane of clinical hea lthy animals, from animals with GK and from animals with pneumonia wit hout any symptoms of GK. The LPS patterns of H.p. strains consists of 2 to 4 bands of high electrophoretical mobility. In all it was possibl e to distinguish seven different LPS electrophoretic profiles. The dis tribution of the H.p. isolates from clinical healthy animals and anima ls with GK or pneumonia to the 7 LPS electrophoretic profiles shows a similar picture. Variation in the growth conditions showed a process o f a standardization of the LPS structure as a result of an increased C O2 atmosphere or lack of O2 respectively.