SYNTHESIS AND BIOLOGICAL PROPERTIES OF 2-MERCAPTOPYRIMIDO-[5,4-C]CINNOLIN-4(3H)-ONES AND THEIR S-ALKYL DERIVATIVES

Authors
MENON RG PURUSHOTHAMAN E
Citation
Rg. Menon et E. Purushothaman, SYNTHESIS AND BIOLOGICAL PROPERTIES OF 2-MERCAPTOPYRIMIDO-[5,4-C]CINNOLIN-4(3H)-ONES AND THEIR S-ALKYL DERIVATIVES, Journal of the Indian Chemical Society, 70(6), 1993, pp. 533-536
Citations number
6
Categorie Soggetti
Chemistry
Journal title
Journal of the Indian Chemical Society → ACNP
ISSN journal
00194522
Volume
70
Issue
6
Year of publication
1993
Pages
533 - 536
Database
ISI
SICI code
0019-4522(1993)70:6<533:SABPO2>2.0.ZU;2-7
Abstract
The synthesis of some hitherto unreported 2-mercaptopyrimido[5,4-c]cin nolin-4(3H)-ones (4) is described. Treatment with alkyl halides under basic conditions yielded the S-alkyl derivatives. The synthesised comp ounds are characterised by spectral and analytical data. Most of the c ompounds of the series exhibit promising antibacterial and antifungal activities.