A pilot study addressed potential effects of long-term exposure to chl
orination products in swimming pools. The indicator compound chlorofor
m was detectable in blood from competitive swimmers in an indoor pool
(mean = 0.89 +/- 0.34 mu g/l; n = 10), but not in outdoor pool swimmer
s. No hepatotoxic effect was indicated by serum glutamate oxaloacetate
transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT) or
gamma-glutamyl transpeptidase (gamma-GT) enzyme levels. beta-2-microgl
obulin, an indicator of renal damage, was significantly elevated in ur
ine samples of the slightly, but significantly, younger indoor swimmer
s. The precise ratio between these 2 possible causes, age and chlorofo
rm exposure, as well as the mechanism of the former, remain to be eluc
idated.