QUINOLINE ALKALOIDS FROM ORIXA-JAPONICA

Six quinoline alkaloids have been newly isolated from a n-hexane extra ct of Orixa japonica stems. Four alkaloids (pteleprenine, N-demethyllu nidonine, N-methylflindersine and 8-methoxy-N-methylflindersine) are d escribed for the first time in this species. Isopteleprenine was obtai ned as a natural product for the first time; (+)-isoptelefolidine is a new compound. Unambiguous H-1 and C-13 NMR assignments of pteleprenin e and isopteleprenine have been achieved.