A NOVEL ROLE FOR THE NITRIC-OXIDE CGMP SIGNALING PATHWAY - THE CONTROL OF EPITHELIAL FUNCTION IN DROSOPHILA

Authors
DOW JAT MADDRELL SHP DAVIES SA SKAER NJV KAISER K
Citation
Jat. Dow et al., A NOVEL ROLE FOR THE NITRIC-OXIDE CGMP SIGNALING PATHWAY - THE CONTROL OF EPITHELIAL FUNCTION IN DROSOPHILA, The American journal of physiology, 266(5), 1994, pp. 180001716-180001719
Citations number
17
Categorie Soggetti
Physiology
Journal title
The American journal of physiology → ACNP
ISSN journal
00029513
Volume
266
Issue
5
Year of publication
1994
Part
2
Pages
180001716 - 180001719
Database
ISI
SICI code
0002-9513(1994)266:5<180001716:ANRFTN>2.0.ZU;2-Y
Abstract
The nitric oxide (NO) signaling pathway plays major roles in the verte brate vascular, nervous, and immune systems. Here we present evidence that all the elements in the NO pathway are present in, and act to con trol epithelial fluid secretion by, the Malpighian tubules of an insec t, Drosophila melanogaster. This finding will allow both a physiologic al and a molecular genetic dissection of the NO pathway in the same ti ssue.