COBALT-CATALYZED 3-COMPONENT COUPLING INVOLVING KETONES OR KETOESTERS, ALDEHYDES AND ACETONITRILE - A NOVEL ONE-POT SYNTHESIS OF BETA-ACETAMIDO KETONES
B. Bhatia et al., COBALT-CATALYZED 3-COMPONENT COUPLING INVOLVING KETONES OR KETOESTERS, ALDEHYDES AND ACETONITRILE - A NOVEL ONE-POT SYNTHESIS OF BETA-ACETAMIDO KETONES, Journal of the Chemical Society, Chemical Communications, (6), 1994, pp. 713-714
Cobalt(II) chloride catalyses one-pot coupling of ketones or ketoester
s, aldehydes and acetonitrile in the presence of acetyl chloride to gi
ve beta-acetamido ketones 3 in good yields.