Cr. Noe et al., CHIRAL LACTOLS .11. A METHOD FOR THE DETE RMINATION OF THE ABSOLUTE-CONFIGURATION OF CHIRAL ALKANOLS, Chemische Berichte, 127(5), 1994, pp. 887-892
Chiral secondary alcohols which are protected with the enantiomericall
y pure lactol 1 or 2 show significant differences in C-13-chemical shi
fts around the glycosidic linkage. An easy method for determination of
the absolute configuration of secondary alcohols based on this fact i
s described.