We examined the optic disk appearance in ocular hypertensive eyes that
had a normal result of conventional computed perimetry. Color stereo-
optic disk photographs of 104 ocular hypertensive subjects and of 216
normal individuals were morphometrically evaluated. In the ocular hype
rtensive eyes as compared to normal eyes, significant differences (P <
.0001) were detected for a smaller area and an abnormal shape of the n
euroretinal rim, larger zones alpha and beta of the parapapillary chor
ioretinal atrophy, a decreased visibility of the retinal nerve fiber l
ayer, and a higher frequency of localized nerve fiber layer defects. T
he variables most useful to indicate optic nerve damage were an abnorm
al shape of the neuroretinal rim and a decreased visibility of the ner
ve fiber layer. The most specific variable was the presence of localiz
ed retinal nerve fiber layer defects. Evaluation of these variables ma
y be helpful for the early diagnosis of glaucoma.