Dj. Damico et al., ERBIUM-YAG LASER PHOTOTHERMAL RETINAL ABLATION IN ENUCLEATED RABBIT EYES, American journal of ophthalmology, 117(6), 1994, pp. 783-790
The erbium:YAG laser has been shown to produce precise tissue ablation
because of the high water absorption of the 2.94-mu m wave-length emi
tted by this laser. We used an experimental system to create lesions o
f various depths in the surface of the rabbit retina in enucleated eye
s in vitro to examine the potential application to maneuvers such as r
etinotomy and the removal of epiretinal membranes in vitrectomy. With
an air/retinal interface, single pulses produced discrete craters in t
he retinal surface with a depth proportional to fluence, ranging from
30 mu m for a pulse of 1.3 J/cm(2) to a full-thickness retinotomy at 3
.9 J/cm(2). An adjacent zone of coagulated tissue ranging in size from
15 to 40 mu m was noted. Multiple pulses had an additive effect. With
a fluid/retinal interface, 20 pulses of 3.6 J/cm(2) produced a full-t
hickness retinotomy, with an adjacent zone of damaged tissue up to 1 m
m, caused by effects of volatilization of intervening fluid. The erbiu
m:YAG laser may have a role in vitreoretinal surgery.