The age-old belief that loss of sperm could be dangerous to health bec
ame a major medical concern throughout the Western world following Cla
ude-Francois Lallemand's inflammatory warnings about the dangers of sp
ermatorrhea. This article investigates the leading role played by Amer
ican neurologic authorities of the mid and late 1800s in their fight a
gainst the cerebral and spinal complications of spermic depletion.