U. Sankilampi et al., EPIDEMIOLOGY OF INVASIVE STREPTOCOCCUS-PNEUMONIAE INFECTIONS IN ADULTS IN FINLAND, Epidemiology and infection, 118(1), 1997, pp. 7-15
Laboratory-based surveillance of invasive pneumococcal infections in a
dults in Finland from 1983 to 1992 identified 862 episodes of pneumoco
ccal bacteraemia and 97 episodes of meningitis. The overall incidence
of invasive pneumococcal infections was 9.1 per 100000 for all adults
per year, but 27.1, 35.8, and 44.5 per 100000 in those aged 65 years o
r over, 75 years or over, and 85 years or over, respectively. Most (99
.7%) of the pneumococcal strains were sensitive to penicillin. Ninety-
five percent of the strains belonged to serogroups/types present in th
e 23-valent pneumococcal polysaccharide vaccine. Group/type distributi
on was different in patients aged 16-64 years compared to those 65 yea
rs or over (P < 0.001), in bacteraemia compared to meningitis (P < 0.0
01), and in the years 1983-7 compared to 1988-92 (P < 0.05).