The knowledge of the skin surface pH-acid mantle is updated. The convi
ction that chronic alkalinization is damaging has been strengthened. E
xtensive skin surface pH data on the skin of non-white people are stil
l missing. In the case of any measurement, the need for extensive infr
astructural research and evaluation by non-parametric methods is empha
sized. Infrastructural studies evaluate the range and change of the me
asured parameters for each test method according to sex, age and body
area, as well as the sensitivity of the method to pharmacological infl
uences. A detailed knowledge of the normal-representative range would
make it possible to select those individuals whose measured parameter
is outside the main 95% of the population; a detailed study of such in
dividuals would be a very effective method of understanding the basic
regulatory mechanism of the measured parameter.