Rw. Kramer et al., HYPOTHYROIDISM IN A DOG AFTER SURGERY AND RADIATION-THERAPY FOR A FUNCTIONAL THYROID ADENOCARCINOMA, Veterinary radiology & ultrasound, 35(2), 1994, pp. 132-136
Hypothyroidism was diagnosed in a dog which had undergone unilateral t
hyroid lobectomy and external beam irradiation (48 Gy in 3 Gy fraction
s) for a functional cystic thyroid adenocarcinoma. Hypothyroidism beca
me biochemically apparent within 4 months of completion of radiation t
herapy, and clinically apparent within 7 months. Clinical signs resolv
ed after thyroid hormone supplementation. The potential for alteration
s in thyroid function should be considered in any animal undergoing ra
diation therapy in which the thyroid gland is included in the radiatio
n field. This potential may be greater if surgery and radiation are co
mbined.