ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY-POSITIVE CRESCENTIC GLOMERULONEPHRITIS AS A COMPLICATION OF TREATMENT WITH PROPYLTHIOURACIL IN CHILDREN

Authors
VOGT BA KIM YK JENNETTE JC FALK RJ BURKE BA SINAIKO A
Citation
Ba. Vogt et al., ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY-POSITIVE CRESCENTIC GLOMERULONEPHRITIS AS A COMPLICATION OF TREATMENT WITH PROPYLTHIOURACIL IN CHILDREN, The Journal of pediatrics, 124(6), 1994, pp. 986-988
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
124
Issue
6
Year of publication
1994
Pages
986 - 988
Database
ISI
SICI code
0022-3476(1994)124:6<986:ACACG>2.0.ZU;2-1
Abstract
Propylthiouracil, which is commonly used in the treatment of hyperthyr oidism, has been associated in adults with antineutrophil cytoplasmic autoantibody, a serologic marker of vasculitis. Severe renal disease h as not been reported as a complication of therapy with this drug. We r eport severe antineutrophil cytoplasmic autoantibody-positive vasculit is in children receiving propylthiourocil, as well as rapidly progress ive crescentic glomerulonephritis after administration of this drug.