ANTIGENICITY AND IMMUNOGENICITY OF EXPERIMENTAL EQUINE INFLUENZA ISCOM VACCINES

Authors
MUMFORD JA JESSETT D DUNLEAVY U WOOD J HANNANT D SUNDQUIST B COOK RF
Citation
Ja. Mumford et al., ANTIGENICITY AND IMMUNOGENICITY OF EXPERIMENTAL EQUINE INFLUENZA ISCOM VACCINES, Vaccine, 12(9), 1994, pp. 857-863
Citations number
12
Categorie Soggetti
Immunology
Journal title
Vaccine → ACNP
ISSN journal
0264410X
Volume
12
Issue
9
Year of publication
1994
Pages
857 - 863
Database
ISI
SICI code
0264-410X(1994)12:9<857:AAIOEE>2.0.ZU;2-C
Abstract
A comparison of the antigenicity and immunogenicity of ISCOM vaccines prepared from equine influenza viruses H3N8 and H7N7 was made with ina ctivated whole-virus vaccines containing equivalent amounts of virus h aemagglutinin. ISCOMs stimulated superior antibody responses in terms of both amount and duration. As with conventional whole-virus vaccines , the levels of antibody to virus haemagglutinin induced by ISCOMs cor related with protection.