Aw. Vantoorenenbergen et al., DIFFERENT PATTERN OF IGE BINDING TO CHICKEN EGG-YOLK BETWEEN PATIENTSWITH INHALANT ALLERGY TO BIRDS AND FOOD-ALLERGIC CHILDREN, International archives of allergy and immunology, 104(2), 1994, pp. 199-203
IgE binding antigens in budgerigar, canary and parrot serum were analy
zed by immunoblotting. With 4 sera from patients with a respiratory al
lergy to birds, a closely related pattern of IgE binding to SDS-PAGE s
eparated sera of the 3 birds was found. In all 3 bird sera a major IgE
binding structure was present with a MW of about 60 kD. The pattern o
f IgE binding to SDS-PAGE separated egg yolk in sera from the patients
allergic to birds, was different from sera of food-allergic children.
Whereas in the bird-allergic patients major IgE binding occurred to a
60 kD component in egg yolk, IgE from food-allergic children was pref
erentially bound to a 35-kD structure in egg yolk.