Occupational asthma after exposure to salbutamol in the pharmaceutical
industry has not been previously reported. The occurrence of occupati
onal asthma is described in two pharmaceutical process workers who wer
e likely to have inhaled doses appreciably in excess of the therapeuti
c dose range. The findings do not lead to an unequivocal conclusion on
the mechanism of the asthma but it was probably a pharmacological con
sequence of high exposure.