RESULTS WITH THE USE OF MITOMYCIN-C

Background Recently, encouraging results with the use of Mitomycin C i n trabeculectomy have been reported. Patients We used Mitomycin C (0.0 28%) during trabeculectomy in 72 eyes of 68 patients. Forty-one eyes h ave already been controlled during 6 months and 19 eyes during 9 month s after the surgery. Results The mean intraocular pressure after 6 and 9 months was respectively 13 +/- 8 mm Hg and 13 +/- 10 mm Hg. The dif ference between these results and the preoperative values (27 +/- 9 mm Hg) were statistically significant after 6 and 9 months (p < 0.001). Despite frequent choroidal detachments (20 eyes), the visual acuity re covered during the follow-up to the preoperative values. Conclusions I n patients with uncertain prognosis for the intraocular pressure after trabeculectomy, the intra-operative application of Mitomycin C seems to improve considerably the operative success rate.