UNUSUAL PRESENTING SIGNS OF RETINOBLASTOM A

Among the 185 retinoblastoma patients seen at the Lausanne Retinoblast oma Clinic from 1963-1993, 24 (14%) first presented with another sign than classical leukocoria (60.5%) or strabismus (21.5%). Most of these atypical signs were related to inflammatory complications of unrecogn ized retinoblastoma; they consisted of low vision (1.5%), hypopyon (2% ), ocular redness and pain (1.5%), ocular redness and buphtalmia (1.5% ), as well as photophobia and headaches (1.5%). The presence of unexpl ained chronic ocular signs during childhood should always raise the po ssibility of an underlying retinal malignancy.