BILATERAL CONJUNCTIVAL AND EYELID TUMOR-A SSOCIATED WITH HUMAN PAPILLOMAVIRUS IN AN IMMUNOCOMPETENT MAN

A 46-year-old white male patient in good general health presented with a bilateral conjunctival and eyelid tumor and a wart at the tip of th e fourth right finger. Impression cytology showed dysplasic cells with loss of cohesion and up to 4 nucleoli per nucleus. The excisional bio psy of the conjunctiva revealed a dysplasic epithelial tissue that all owed the diagnosis of papilloma with parts of conjunctival intraepithe lial neoplasia (CIN). Papilloma has been associated with Human Papillo mavirus (HPV). The molecular hybridization analysis using PCR revealed that HPV was present in the eye tumor and in the wart, but the viral type was not the same. Treatment of the eye tumor with excision and lo w temperature cryocoagulation was successful.