K. Sekihara et al., REDUCTION OF BRAIN NOISE INFLUENCE IN EVOKED NEUROMAGNETIC SOURCE LOCALIZATION USING NOISE SPATIAL CORRELATION, Physics in medicine and biology, 39(6), 1994, pp. 937-946
In magnetoencephalographic measurements, magnetic fields caused by spo
ntaneous brain activities not related to the neural activities under s
tudy are often referred to as brain noise. This is because the accurac
y in neural source localization is considerably degraded by such spont
aneous neuromagnetic fields. This paper reports the experimental resul
ts of applying the previously proposed noise covariance method to redu
cing the degradation caused by brain noise and to improving the accura
cy in localizing auditory-evoked neural sources. Firstly we present th
e results of our experiments using measured brain noise and computer-g
enerated signal fields. These results confirm that the covariance meth
od can, in principle, improve the accuracy of evoked neural source loc
alization. Next, the method was applied to source localization for act
ual neuromagnetic fields evoked by speech sounds. The results obtained
strongly suggest that the method is effective in processing actual ev
oked neuromagnetic data.