Purpose: Controversy exists regarding the extent of vascular reconstru
ctive surgery in the presence of unilateral symptomatic iliac obstruct
ive disease. This study reviews the results of unilateral iliac recons
truction, with special emphasis on the need for consecutive contralate
ral intervention. Methods: The outcomes of 184 unilateral and 350 aort
obilateral reconstructions for obstructive disease performed during th
e same period were retrospectively analyzed. Treatment allocation was
based on hemodynamic parameters. Unilateral reconstruction was perform
ed by a way of a retroperitoneal approach through a pararectal incisio
n and bilateral reconstruction by way of a transperitoneal approach th
rough a midline abdominal incision. Results: Symptom relief, improveme
nt of noninvasively measured parameters, and graft patency were simila
r after unilateral and bilateral reconstruction. Both groups had a 10-
year primary patency rate greater than 80%. There were no differences
in morbidity rate, although respiratory complications occurred more of
ten after bilateral reconstruction. Mortality rates were 1.6% after un
ilateral reconstruction and 4.9% after bilateral reconstruction. Secon
dary contralateral reconstruction was performed in only 6% of the pati
ents who underwent an initial unilateral operation. Conclusions: The u
nilateral vascular reconstruction for iliac obstructive disease is a w
ell-tolerated procedure with an excellent long-term outcome. It is a v
aluable alternative to conventional aortobilateral reconstruction in c
arefully selected patients. Prophylactic reconstruction of an asymptom
atic iliac stenosis without signs of significant hemodynamic impairmen
t is most often not indicated.