N. Carp et al., STUDY BY ULTRAVIOLET-VISIBLE DERIVATIVE SPECTROPHOTOMETRY OF SOME ANTIBIOTICS .1. MOLECULAR-INTERACTIONS OF BENZYLPENICILLIN IN AQUEOUS-SOLUTION, Analyst, 119(5), 1994, pp. 1087-1091
The effect of concentration on the characteristics of the ultraviolet-
visible (UV/VIS) absorption spectra of benzylpenicillin sodium in aque
ous solutions was studied. In order to separate the overlapped bands,
derivative spectrophotometry was used. The UV-VIS spectral behaviour i
n three concentration ranges was distinguished, and was confirmed by s
pectrofluorimetric, specific viscosity and surface tension measurement
s.