LATE SEQUELAE IN CHILDREN TREATED FOR BRAIN-TUMORS AND LEUKEMIA

Forty-two survivors treated at an age of 2-16 years for brain tumors o r leukemia were, 4-21 years after treatment, subjected to an extensive follow-up investigation, including physical examination and interview ; 35 of them also had endocrinological and 33 psychological evaluation . Hormonal deficiencies were found in about two-thirds of patients and were most common in those treated for brain tumors. The great majorit y had verbal intelligence quotient (VIQ) within normal range. Also, th e performance intelligence quotients (PIQ) were normal in most patient s. However, the results suggested that the primary intellectual capaci ty in children treated for cancer was not being fully utilized, their PIQ being on the average higher than their VIQ; this tendency was espe cially pronounced in the leukemia patients.