SYNTHESIS OF L-O-PHOSPHOHOMOSERINE AND ITS C-3 CHIRALLY DEUTERIATED ISOTOPOMERS - PROBES FOR THE PYRIDOXAL-PHOSPHATE DEPENDENT THREONINE SYNTHASE REACTION

Authors
BARCLAY F CHRYSTAL E GANI D
Citation
F. Barclay et al., SYNTHESIS OF L-O-PHOSPHOHOMOSERINE AND ITS C-3 CHIRALLY DEUTERIATED ISOTOPOMERS - PROBES FOR THE PYRIDOXAL-PHOSPHATE DEPENDENT THREONINE SYNTHASE REACTION, Journal of the Chemical Society, Chemical Communications, (7), 1994, pp. 815-816
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
7
Year of publication
1994
Pages
815 - 816
Database
ISI
SICI code
0022-4936(1994):7<815:SOLAIC>2.0.ZU;2-3
Abstract
A short efficient synthesis of the threonine synthase substrate L-O-ph osphohomoserine and its C-3 chirally deuteriated isotopomers is descri bed; the route also provides access to L-homoserine and its C-3 chiral ly deuteriated isotopomers in high yield.