The polarization of the embryonic axes is a key event in embryogenesis
, being one of the earliest manifestations of the shape and form of th
e organism. The acquisition of polarity by individual blastomeres is o
ne of the earliest indicators of commitment to a particular pathway of
differentiation. These phenomena have been studied in the development
of C. elegans both at the cellular and organismal level. This review
summarizes what is known about how polarity is established in the blas
tomeres of this organism, how the division axes of polarized cells are
determined, and how the embryonic axes are set up.