PROPERTIES OF THE TRANSIENT POTASSIUM CURRENTS IN CEREBELLAR GRANULE CELLS

Macroscopic potassium currents were studied in cell-attached and insid e-out patches from rat cerebellar granule cells. They were related wit h transient I-A type potassium channels. Currents activated rapidly at potentials higher than -40 mV and did not inactivate completely. The magnitude of the current diminished when the membrane patches were exc ised. No differences in the activation and inactivation properties wer e found between patches in the integral cells and cell free membrane p atches. A biophysical description of the currents is presented.